What it is
GLP-1 receptor agonists are prescription medicines that act on the receptors for GLP-1 (glucagon-like peptide-1), a gut hormone involved in appetite and blood sugar control. Clinicians prescribe them as one part of a weight-management plan that also includes nutrition, activity and regular follow-up.
A sublingual preparation is held under the tongue instead of being injected. There is no FDA-approved sublingual GLP-1 product, so this dosage form is available only as a compounded preparation. Your prescriber decides whether it is appropriate for you.
What you receive
- Sublingual preparation in a metered oral dispenser, for consistent dosing.
- Strength and schedule exactly as written by your prescriber.
- A label with directions, storage conditions and a beyond-use date.
How to get it
- Patients: ask your prescriber to send the prescription to AccuMix Pharmacy by e-prescription or fax. No prescriber yet? Contact us and we can coordinate with a licensed telehealth provider in your state.
- Providers and clinics: see our Providers page for what to include on the prescription, or call 866-817-5303 for a pharmacist consult.
We dispense only on a valid prescription for a named patient; nothing is sold through this website. Our turnaround time is 24 hours, and we ship to the 37 states and Washington, DC where we hold a license.
How it is made
Compounded under USP <795>, with USP <800> controls for hazardous ingredients, by a team led by board-certified pharmacists. Ingredients come from FDA-registered suppliers and are verified against a certificate of analysis. A pharmacist checks each step, and every preparation is traceable by lot.
Safety and what to expect
- Follow your label for how to place the dose under the tongue, how long to hold it there, and when you may eat or drink.
- Use exactly as prescribed and do not change your dose on your own.
- The most common side effects of medicines in this class are nausea, vomiting, diarrhea, constipation and stomach pain. They are most likely when treatment starts or the dose goes up.
- FDA-approved medicines in this class carry a boxed warning about thyroid C-cell tumors. Tell your prescriber about any personal or family history of medullary thyroid cancer or MEN 2, pancreatitis or gallbladder disease, and if you are pregnant, planning a pregnancy or breastfeeding.
- Sublingual and injectable doses are not interchangeable. Do not switch between forms unless your prescriber changes the prescription.
- Severe stomach pain, vomiting that does not stop, or signs of an allergic reaction need prompt medical attention.
Storage
Follow the storage directions and the beyond-use date (BUD) printed on your label, including refrigeration if indicated. Keep all medications out of the reach of children and pets.
Common questions
Can I switch from the injection to the sublingual form?
Only if your prescriber writes a new prescription. The dose is different for each route.
Why would a prescriber choose a sublingual form?
Usually because a patient cannot or prefers not to self-inject. Your prescriber weighs that against your history and response to treatment.
Is there a capsule?
Yes. See Oral GLP-1 Capsules.
Compounded medications are not reviewed or approved by the FDA. AccuMix Pharmacy is a 503A compounding pharmacy and compounds only after receiving a valid prescription for an individual patient. This page is general information, not medical advice. Your prescriber decides whether this therapy is right for you.
More about Weight Management Compounding at AccuMix Pharmacy.
